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Research published in The AAPS Journal confirms subcutaneous injections bypass enzymatic degradation and first-pass metabolism, resulting in higher systemic exposure and tighter control over therapeutic concentrations

Visible improvement often apparent by month 2-3 with continued gains through month 12 and beyond

Normal saline (0.9% NaCl) is sometimes mentioned as an alternative

[DOI] [PubMed] [Google Scholar] 12.Kjell J, Olson L

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